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Steroid-induced diabetes, or steriodogenic diabetes, is defined as “glucose intolerance or overt hyperglycemia induced by glucocorticoids” (Dorland’s Medical Dictionary).

Glucocorticoids and Indications for Use

Glucocorticoids (GCs) are a class of steroids that work to suppress the immune system by mimicking cortisol, which is produced in the adrenal complex. They also have anti-inflammatory properties. Immunosuppressants and anti-inflammatories play a key role in the treatment of various conditions, ranging from asthma and allergies, to arthritic diseases, such as rheumatoid arthritis, to more complex immunologic syndromes, such as cystic fibrosis, lupus, and multiple sclerosis.

Glucocorticoids are also useful in immune system suppression in patients after organ transplants, and inflammation reduction in patients undergoing chemotherapy. Prednisone, dexamethasone, triamcinolone, and methylprednisolone are a few GCs utilized for the above conditions. Asthma, which is inflammation of the airway, can be very successfully treated with GCs because they reduce inflammation in the bronchi and lower the body’s immunologic response causing the inflammation.

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